04/12/2025 – MSK and Ortho

Question Easy: A 30-year-old woman presents to her GP with pain in her right wrist after tripping and falling on an outstretched hand. She describes the pain as sharp and reports some swelling but no visible deformity. An X-ray is ordered to rule out any fractures. Which bone is most commonly fractured in such a scenario? 🖐️

A) Scaphoid
B) Lunate
C) Triquetrum
D) Hamate
E) Capitate

Question Medium: A 65-year-old man visits the clinic complaining of pain and stiffness predominantly in the morning, lasting over an hour. He also mentions swelling in the small joints of both his hands. Blood tests reveal elevated rheumatoid factor and anti-CCP antibodies. What is the first-line treatment for his condition according to NICE guidelines? 💊

A) Methotrexate
B) Hydroxychloroquine
C) Sulfasalazine
D) Prednisolone
E) Naproxen

Question Hard: A 45-year-old woman with a past history of rheumatoid arthritis presents with sudden onset of severe pain in her right knee, which is warm and swollen. Joint aspiration reveals cloudy synovial fluid. The fluid’s leucocyte count is very high, predominantly polymorphonuclear cells. What is the most likely diagnosis? 🚨

A) Gout
B) Pseudogout
C) Septic arthritis
D) Osteoarthritis flare
E) Reactive arthritis

Explanations & Answers:

Question Easy Answer: A) Scaphoid

Question Easy Explanation: The scaphoid bone is the most commonly fractured carpal bone when a person falls on an outstretched hand. This is due to its anatomical position and the force transmission during falls. Early identification and treatment of scaphoid fractures are critical to prevent complications like avascular necrosis.

Question Medium Answer: A) Methotrexate

Question Medium Explanation: Methotrexate is recommended by NICE as the first-line disease-modifying anti-rheumatic drug (DMARD) for patients with rheumatoid arthritis. It is an effective therapy in controlling symptoms and slowing disease progression, and is typically used in combination with other medications when necessary.

Question Hard Answer: C) Septic arthritis

Question Hard Explanation: The clinical presentation of acute monoarthritis with a high leukocyte count in the synovial fluid, predominantly neutrophils, suggests septic arthritis. This condition requires urgent medical attention and often necessitates antibiotic treatment and sometimes surgical intervention to prevent joint damage.

Medical fact of the day: In the UK, osteoarthritis is one of the most common forms of arthritis, affecting over 8 million people. It predominantly affects the knees, hips, and small joints of the hands, leading to significant impact on daily activities.

Quote of the day: “In the tapestry of healthcare, it’s not the sole thread, but the unique weave of compassion and knowledge that defines a healer’s journey.” 🌟