07/01/2026 – Endo and Neuro

Question Easy:
A 28-year-old woman has been diagnosed with a prolactinoma. She presents with complaints of amenorrhea, headaches, and galactorrhea. What is the first-line treatment? 😊
A) Bromocriptine
B) Cabergoline
C) Surgery
D) Radiotherapy
E) Observation

Question Medium:
A 34-year-old man presents with a history of excessive sweating, weight loss, and palpitations. On examination, you note exophthalmos. His thyroid function tests are consistent with hyperthyroidism. What is the most likely cause of his condition in the UK? 😯
A) Toxic multinodular goitre
B) Graves’ disease
C) Thyroid adenoma
D) Subacute thyroiditis
E) Iodine-induced hyperthyroidism

Question Hard:
A 60-year-old man arrives at the emergency department with acute confusion, headache, and visual disturbances. His blood pressure is 210/130 mmHg. Neuroimaging shows bilateral oedema in the occipital lobes. What is the most likely diagnosis? 🧠
A) Ischaemic stroke
B) Subarachnoid haemorrhage
C) Posterior reversible encephalopathy syndrome (PRES)
D) Intracerebral haemorrhage
E) Migraine with aura

Explanations & Answers:

Question Easy Answer: B) Cabergoline
Question Easy Explanation: Cabergoline is the first-line treatment for prolactinomas as per NICE guidelines due to its favorable side effect profile compared to bromocriptine. It’s effective in reducing tumor size and prolactin levels.

Question Medium Answer: B) Graves’ disease
Question Medium Explanation: Graves’ disease is the most common cause of hyperthyroidism in the UK. It is an autoimmune disorder characterized by features such as exophthalmos and diffusely enlarged thyroid gland, aligning with the patient’s presentation.

Question Hard Answer: C) Posterior reversible encephalopathy syndrome (PRES)
Question Hard Explanation: PRES is characterized by headache, seizures, and visual changes often due to acute hypertension. Neuroimaging showing bilateral occipital oedema aligns with this diagnosis. Management involves controlling the blood pressure.

Medical fact of the day: Did you know? In the UK, the prevalence of primary hyperparathyroidism is about 1-7 per 1,000 adults, with higher incidence in older women. Early detection and management can prevent complications such as osteoporosis and renal stones.

Quote of the day: “In the journey of healing, every step forward starts with courage, every act of care, with compassion. Keep shining the light of hope in every life you touch.” ✨