15/11/2025 – Obstetrics and Gynaecology

Question Easy:

A 28-year-old woman presents to the GP with heavy menstrual bleeding and lower abdominal pain for the last three months. Her periods are regular, but the bleeding has increased. What is the first-line treatment option for managing her symptoms? 🤔

A) Levonorgestrel-releasing intrauterine system (LNG-IUS)
B) Combined oral contraceptive pill
C) Tranexamic acid
D) Nonsteroidal anti-inflammatory drugs (NSAIDs)
E) Oral progestogens

Question Medium:

A 34-year-old woman, 28 weeks pregnant, presents with severe itching all over her body, especially on the palms and soles. There is no rash present. Her liver function tests show elevated bile acids. Which condition is most likely responsible for her symptoms?

A) Intrahepatic cholestasis of pregnancy
B) Preeclampsia
C) Acute fatty liver of pregnancy
D) Obstetric cholestasis
E) Hyperemesis gravidarum

Question Hard:

A 45-year-old woman presents to the clinic with postcoital bleeding and an abnormal Pap smear showing high-grade squamous intraepithelial lesion (HSIL). Colposcopy reveals a suspicious lesion on the cervix. What is the most appropriate next step in management?

A) Repeat Pap smear in 6 months
B) LEEP (Loop Electrosurgical Excision Procedure)
C) HPV vaccination
D) Hysterectomy
E) Observation and follow-up

Explanations & Answers:

Question Easy Answer: A) Levonorgestrel-releasing intrauterine system (LNG-IUS)

Question Easy Explanation: The NICE guidelines recommend the LNG-IUS as the first-line treatment for heavy menstrual bleeding where contraception is also required. It is highly effective in reducing menstrual blood loss and improving symptoms.

Question Medium Answer: A) Intrahepatic cholestasis of pregnancy

Question Medium Explanation: Intrahepatic cholestasis of pregnancy (ICP) is characterised by intense pruritus, particularly on the palms and soles, with elevated bile acids. It is important to monitor and manage this condition to prevent potential adverse outcomes for the baby.

Question Hard Answer: B) LEEP (Loop Electrosurgical Excision Procedure)

Question Hard Explanation: With the presence of a high-grade squamous intraepithelial lesion and a suspicious lesion on colposcopy, LEEP is the appropriate next step. This procedure allows for both diagnostic and therapeutic intervention by excising the abnormal tissue.

Medical fact of the day: The UK has a routine HPV vaccination programme that significantly reduces the incidence of cervical cancer, making it one of the few cancers preventable by vaccination. 💉

Quote of the day: “In the midst of every challenge, lies caring hands and hearts ready to heal. Embrace each day with compassion and patience.” 🌟