23/09/2025 – Renal and Urology

Question Easy:
A 35-year-old man presents with dysuria, increased urinary frequency, and suprapubic discomfort. He denies any penile discharge. His urine dipstick test shows the presence of nitrites and leukocytes. What is the most likely diagnosis? 🚽

A) Urethritis
B) Cystitis
C) Pyelonephritis
D) Prostatitis
E) Renal calculi

Question Medium:
A 60-year-old woman with a history of hypertension presents with severe back pain radiating to the groin and microscopic hematuria. An ultrasound reveals a 6mm calculus in the ureter. Which of the following is the first-line management option? 🩺

A) Extracorporeal shock wave lithotripsy (ESWL)
B) Observation and increased fluid intake
C) Ureteroscopy
D) Open surgical removal
E) Percutaneous nephrolithotomy

Question Hard:
A 50-year-old gentleman presents with recurrent episodes of macroscopic hematuria. He has a 20-year history of smoking and intermittent episodes of right-sided flank pain. A CT urogram reveals a solid mass in the right kidney. What is the most appropriate initial investigation to further assess this mass? 📊

A) MRI of the abdomen
B) Renal biopsy
C) PET scan
D) Cystoscopy
E) Magnetic resonance angiography (MRA)

Explanations & Answers:

Question Easy Answer: B) Cystitis
Question Easy Explanation: The symptoms of dysuria, increased frequency, and suprapubic discomfort are classic signs of cystitis, especially when associated with nitrites and leukocytes on a urine dipstick, suggestive of a bacterial lower urinary tract infection. According to NHS guidelines, this aligns with uncomplicated urinary tract infection (UTI) in a young male.

Question Medium Answer: A) Extracorporeal shock wave lithotripsy (ESWL)
Question Medium Explanation: For ureteric stones that are around 6mm, NICE guidelines recommend ESWL as the first-line management if the stone is unlikely to pass naturally, particularly if causing significant symptoms. Increased fluid intake may be recommended for smaller stones or when waiting for ESWL.

Question Hard Answer: A) MRI of the abdomen
Question Hard Explanation: In cases of renal masses, MRI can help in characterizing the mass further, distinguishing between benign and malignant lesions especially when CT has already identified the presence of a mass. Biopsy is generally avoided due to risk of seeding and diagnostic limitations in such cases.

Medical fact of the day: The kidney produces a hormone called erythropoietin, which is essential for the production of red blood cells. Patients with chronic kidney disease often have anemia because of reduced production of this hormone, and may require synthetic erythropoietin as part of their management.

Quote of the day: “Every drop of compassion you share is a ripple in the stream of healing.” 🌊