25/08/2025 – Cardio and Respiratory

Question Easy:
A 28-year-old woman presents with chest pain that worsens when lying down and improves when sitting up. She’s had a fever over the past few days. On auscultation, a “friction rub” is heard. What is the most likely diagnosis? 😷
A) Myocardial infarction
B) Pericarditis
C) Pulmonary embolism
D) Pneumothorax
E) Aortic dissection

Question Medium:
A 65-year-old man with a history of hypertension and type 2 diabetes presents with increasing shortness of breath and ankle swelling over the past few weeks. On examination, he has jugular venous distension and bilateral lung crackles. What is the most appropriate first-line management in this case, according to NICE guidelines? 💊
A) Beta-blockers
B) ACE inhibitors
C) Loop diuretics
D) Calcium channel blockers
E) Thiazide diuretics

Question Hard:
A 54-year-old man with a history of chronic obstructive pulmonary disease (COPD) presents with acute respiratory distress. His arterial blood gases show pH 7.25, PaCO2 8.2 kPa, and PaO2 7.0 kPa. Based on the BNF guidelines, which of the following treatments should be prioritized in managing this patient? 🚑
A) High-flow oxygen therapy
B) Non-invasive ventilation (NIV)
C) Antibiotics
D) Inhaled corticosteroids
E) Intravenous aminophylline

Explanations & Answers:

Question Easy Answer: B) Pericarditis
Question Easy Explanation: The presentation of chest pain that is positional, fever, and a pericardial friction rub is classic for pericarditis. Unlike myocardial infarction, pericarditis pain typically improves with sitting forward. NICE guidelines suggest managing mild cases with NSAIDs and colchicine.

Question Medium Answer: C) Loop diuretics
Question Medium Explanation: The symptoms and signs indicate heart failure, for which loop diuretics like furosemide are the first-line treatment according to NICE guidelines. They help reduce fluid overload, improve symptoms, and can be quickly effective in acute settings.

Question Hard Answer: B) Non-invasive ventilation (NIV)
Question Hard Explanation: The arterial blood gas indicates respiratory acidosis with CO2 retention, typical of a COPD exacerbation. According to BNF guidelines, NIV is indicated to manage CO2 retention and correct acidosis, aiming to improve ventilation and oxygenation while avoiding the complications of invasive mechanical ventilation.

Medical fact of the day: Did you know that in the UK, asthma affects approximately 5.4 million people, meaning 1 in every 12 adults? It’s a major cause of hospital admissions, but with the use of preventer inhalers and management plans, many can lead a symptom-free life. 🌬️

Quote of the day: “In the journey of healing, every step taken with care creates ripples of hope. Keep moving forward with kindness and compassion.”