29/09/2025 – Cardio and Respiratory

Question Easy:
A 50-year-old man presents to the GP with shortness of breath and a chronic cough producing white sputum. He has a 30-pack-year smoking history. On examination, he has wheeze on auscultation but no peripheral edema. What is the most likely diagnosis? 🚬

A) Asthma
B) Bronchiectasis
C) Chronic Obstructive Pulmonary Disease (COPD)
D) Lung cancer
E) Heart failure

Question Medium:
A 70-year-old woman presents with increasing shortness of breath, orthopnea, and paroxysmal nocturnal dyspnea. On examination, she has an elevated jugular venous pressure, bilateral basal crackles, and pitting edema of the ankles. Which of the following medications should be considered first-line treatment for fluid overload in this condition? 💧

A) Spironolactone
B) Furosemide
C) Bisoprolol
D) Lisinopril
E) Digoxin

Question Hard:
A 30-year-old man presents with an acute onset of chest pain and dyspnea. The pain is sharp, left-sided, and worsens with inspiration. He recently returned from a long-haul flight. Examination reveals a swollen, tender left calf. What is the most appropriate immediate investigation to confirm the suspected diagnosis? ✈️

A) D-dimer test
B) ECG
C) Chest X-ray
D) CT Pulmonary Angiography (CTPA)
E) Arterial blood gas

Explanations & Answers:

Question Easy Answer: C) Chronic Obstructive Pulmonary Disease (COPD)
Question Easy Explanation: This patient’s long smoking history and presentation of chronic cough with sputum production are classic signs of COPD. NICE guidelines recommend considering this diagnosis primarily in smokers with such symptoms. Asthma is less likely at this age without prior history, and lung cancer typically presents with more alarming symptoms or hemoptysis.

Question Medium Answer: B) Furosemide
Question Medium Explanation: The symptoms and signs indicate heart failure with consequent fluid overload. According to NICE guidelines, a loop diuretic like furosemide is the first-line treatment to manage fluid retention and reduce peripheral edema and pulmonary congestion.

Question Hard Answer: D) CT Pulmonary Angiography (CTPA)
Question Hard Explanation: The clinical scenario is highly suggestive of a pulmonary embolism, especially given his recent long-haul flight and symptoms of deep vein thrombosis. CTPA is the definitive test to confirm the presence of pulmonary emboli, as per NHS guidelines.

Medical fact of the day: The UK has one of the highest incidences of asthma in the world, affecting approximately 8 million people. Measures such as smoking cessation 🚭 and pollution control are crucial in managing and reducing the impact of respiratory diseases.

Quote of the day: “In the tapestry of healthcare, every thread of compassion weaves strength into the fabric of healing.” 🌟